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Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation. May 2, 2009 What do you think of the research of Siliciano and Pomerantz ? HIV-1 latency in resting CD4+ T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy (HAART). Eliminating the latent HIV-1 reservoir may require the reactivation of viral gene expression in latently infected cells. Siliciano and Pomerantz have found a way to reactivate latent HIV-1 in cells from patients on HAART without causing significant T cell activation. http://www.pnas.org/content/106/15/6321.short I'm sure that they are very close to the cure. |
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| Response from Dr. Young
 Hello and thanks for your post. It's a very long way from early clinical science to a drug, never mind being "very close to the cure". Even for less revolutionary discoveries, it can take many years of testing and clinical trials to establish effectiveness and safety. Nevertheless, here's hoping that with each discovery, we are closer. BY | ||||||||
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