Apr 29, 2009
DEAR SIR HOW UNDERSTAND POSATIVE CHANGE TO NAGATIVE? HOW LONG I NEED TO WAIT FOR TEST BECOME NEGATIVE? IS IT MAGER LIKE HIV ?
| Response from Dr. McGowan
The TPHA test is a test for exposure to syphilis, the levels (called titers) will not change after treatment and this test should not be used to monitor response to treatment. It will remain positive for life after a single episode of syphilis. Other tests, called non-treponemal tests (such as the RPR or the VDRL) will go up with active infection and down after treatment. Occasionally they may also remain positive at a low level for life. If the titers of the RPR or VDRL have not decreased significantly (or have increased) by 6 months after treatment, then a second course of treatment may be needed. It is possible for a person to be re-infected.
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