|Timing of meds
Apr 24, 2009
Hello and let me also add my thanks for this incredible service. I have a question about the timing of taking one's meds, similar but not quite the same as a couple you've recently answered.
I have just started on Atripla about a week ago and, pursuant to the general recommendation, am taking it at bedtime. I am wondering about the half life of the medication in the body and how much flexibility one has in the timing. I don't go to bed the same time each night and, from what I've read so far, assume that + or - 2 hours or so is not a big deal. But, just how far can you push it? Is 10pm one night and 2am the next too big a swing? They say if you miss a dose then don't try to make it up, just go on to the next regular dose. But, how long a time period is considered a missed dose after which you should just go on to the next one? 6 hrs? 8 hrs? 10? My guess is that the scientific answer is going to depend on a number of factors such as viral load, weight, metabolism, etc., but I'm just trying to not screw this up. Thanks for your help.
| Response from Dr. Young
Hello and thank you for both your post and thoughts.
One need not live by the clock when taking HIV medications- it's perfectly ok to have a +/- 4 hour change in doses. There isn't good data on just how far to push it; but so long as most of the doses are around the same time, any single variation probably won't have significant consequences.
Be well, BY
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