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re: started kaletra
Jan 26, 2009

Hi doctor,

Yes, i wasn't entirly clear :) I'm on kaletra/emtriva/viread, I haven't missed a single dose. I take 4 kaletra, 1 emtriva, 1 viread each night before sleep (so once daily, i was treatment naive). There's a 4h window in which i take my meds (say 23h to 03h, i go to bed late). Baseline resistence tests were performed right after i was diagnosed (soon after seroconversion) and showed wild type back then... i have to be honest: i do practice serosorting and sometimes unprotected. My VL has always been low, my CD4 has always been rather high, though the CD4% decreased to 17% over time.

Hope this clarifies my post! thanks again for the great job you guys do...

Response from Dr. Young

Hello again; thanks for your follow up and kind words.

Certainly sounds like you're on a reasonable first-line regimen and are very adequately adherent.

With the baseline resistance test, there should be no reason why you won't have a full response. However, I am concerned (especially in light of your tepid viral load response so far), that your unprotected serosorting could have exposed you to resistant virus.

At this point, there's no recommendation to change your regimen, but I'm with your doctor in tightening up the monitoring tests to monthy (as he or she has). I'll continue be the advocate for protected sex, since your situation raises this issue of risks (and the possibility of getting other sexually transmitted infections).

Stay in touch, let us know how things are going.

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