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just started taking atripla
Jan 3, 2009

I just started treatment (atripla) 2 weeks ago. Usually I suffer no side effects from any medications but this is kicking my butt!!! I can't sleep - I toss and turn all night - vomiting in the morning and in a fog until noon. I had hives for a few days but I think they're done with now. Will I eventually be able to sleep?? I work full time and run a household with 2 teenagers and this has just really turned my world upside down. Thanks Lori

Response from Dr. Young

Hello Lori and thanks for your post.

It sounds like you're having a particularly bad experience with the efavirenz part of Atripla. Side effects that last until noon, especially after two weeks of treatment, suggest to me that you may very well need a change in medication.

I'd be curious to know if you take your medication with food (or eat late at night), or if you're an African-American-- both have been associated uncommonly with more severe reactions to efavirenz.

I'd certainly talk to your doctor about your symptoms. If they don't improve, don't fret-- there are very well tolerated alternatives (you can surf our forum here at for other's experiences).

Be well, BY

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