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Drug resistance
Oct 14, 2008

Hi Doctor. Thanks for your assistance. you make such huge difference in people's life. If one takes his/her Atripla everyday, never miss a dose, yet take the pill at different times in the evening. That is 3 hourly difference. sometimes one take it at 7pm, other times at 9pm on other occassions at 10pm. Would that practice risk resistance? or should one take it exactly at a specific hour in the evening? Would a 3 hour variation make a difference, given the fact that one never miss a dose each evening. Thanks.

Response from Dr. Young

Thanks for your post.

I try to get my patients to take their medications with a daily routine- in the case of any efavirenz-based treatment, this means around bedtime. There's nothing critical about being within minutes are even a few hours- so in your case a 3 hour variation in timing shouldn't be an issue. As you correctly point out, the real issue is avoiding missing any doses.

I hope this helps. Be well,

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