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RBC and WBC going down even after starting HAART
Jun 6, 2008

My wife is on treatment of Duovir and Effavir since 3/05/08. She is also on anti-tuberclosis treatment since 9/01/08.Her general condition has improved. She has gained about 2.5 kg weight after HAART. However her WBC has come down from 3.83(1/04/08) to 2.97(3/06/08). Her RBC has come down from 4.26 to 3.61 and LYM.has gone up from 71.3 to the same period.Hb has come down from 11.5 to 10.4. Tests have been done in the same laboratory. Before starting treatment her CD4 count was 62. Does it mean that HIV has not been controlled or she has some othe disease

Response from Dr. Young

Thanks for your post.

I'm heartened to hear that your wife is generally doing well with both her tuberculosis and HIV. Duovir (also known as Combivir or AZT+3TC) can cause modest decreases in some of the blood cell counts. Based on what you've listed, I don't think that these slight decreases are of any real significance, nor does this mean that HIV hasn't been controlled.

The best way to assess this question is through a viral load test (if available), otherwise, knowing that she continues to feel well and has gained weight gives very strong evidence of effectiveness.

Best of luck to you and her, BY

should I start meds?

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