Feb 28, 2008
Hello Dr. Young,
my initial VL was around 450,000. I have been for 5 months on Boosted Telzir and Kivexa. I haven't gone undetectable according to my last 2 labs which scored around 200 VL. I have made resistance testing before and supposedly had non!
I'm seeing my doctor in 2 weeks with new test results before we consider changing treatment. What could be the reason for this faliure? and what should our strategy be?
My risk involved a girl who was in contact with people of eastern african origin. I've always thought of the rare Hiv1/HIV2 coinfection, could be a possibility? how can we verify that? I did all viral tests including phnotypes and I have HIV-1 subtype D. Could those tests detect HIV-2 if this was not intended?
sorry for the long post, but as you can see I need to get a grip on why my first regimen unexpectedly failed.
| Response from Dr. Young
First off, your antibody tests should have distinguished between HIV1 and HIV2 infection.
Second, since you started HIV treatments with a quite high HIV1 viral load, it's not surprising (nor unexpected) that you might not have reached a viral load of less than 50 copies yet. You do not, in my view, have treatment failure. If I were your doctor, I would continue to monitor your adherence and viral load- perhaps only to move the interval of testing to every other month, just to be sure that the viral load eventually reaches the mind-at-ease level of less than 50.
I hope this helps. BY
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