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Good Cocktail? (Cont'd)

Jan 21, 2008

Hi Dr. Young,

My doctor added Zerit when, after first going on Atripla (Sustiva and Truvada) alone in 2005, my viral load went up a little from undetectable. I have no history though of drug resistance. My only prior cocktail was Trizivir which I stopped after 3 years because of fatigue, muscle weakness, and Nausea.

Since taking Atripla, my CD4 count is usually around 500 and my viral load (aside from the one test mentioned above) has been undetectable.

Again, thanks

Response from Dr. Young

Thanks for your follow up.

While much depends on how much and for how long the viral load went up, the idea of intensifying your drug regimen makes some sense.

That said, I'd be inclined to think that adding a 4th drug to your regimen does little for potency. Certainly, if your tolerating the medications well at this point, there is little urgency to switch anything. In the least, I'd likely recommend being on the lower dose of d4T, 30 mg (instead of 40 mg) twice daily.

Best of health, BY

Starting Med at 350? 250? 200?
Reyataz/Norvir or Kaletra?

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