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Low Platelets and Spleen Removal
Nov 4, 2007

My brother is HIV positive and has had a very low (3-4000) platelet count for over a month. His dr. is insisting that the only course of treatment left is to remove his spleen, they've already tried multipe transfusions, prednisone, and HIV meds. What can we expect pre- and post-surgery in regard to his HIV?

Response from Dr. Wohl

Removing the spleen is the last resort but it seems like nothing else has worked. The surgery is not that difficult or dangerous in most people. If his CD4 cell count is not very low, risk for complications should not be much different than those without HIV. The reason this works is that the spleen filters out the platelets that are being tagged with antibodies the body makes during HIV.


TMC278, CD4 vs. %
Immediate meds after exposure

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