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what medicines
Oct 14, 2007

Diagonised positive only 20 days back, my friend has lost a lot of weight . CD 204 , what medicines to start with ?

Response from Dr. Young

Thank you for your post.

There's a lot of things to consider in the managment of persons with recently diagnosed HIV disease (not just medications). Things like laboratory assessments, education, preventive vaccinations, etc.

With regard to medications, any selection of medications today requires an understanding of the virus' drug resistance pattern. Depending on the city, from 10-30% of persons acquire virus with some degree of drug resistance. Knowing this pattern is essential (and recommended by government guidelines across the world) in choosing medications.

There are guidelines that doctors use to assist in making first-line treatment decisions. In short, all current guidelines recommend the use of 2 NRTI (nuke) drugs in combination with either a NNRTI (non-nuke) or ritonavir-boosted PI (protease inhibitor). The choice among these regimens is based on a number of medical characteristics (of the patient, virus and regimen)- we live in an envirnoment where we can individualize care, where understanding these individual parameters can make regimens more likely to succeed and be better tolerated.

I'd ask you to spend some time looking over our forum- you'll find plenty of Q&A on this point.

Best of health, BY



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