Lexiva Boosted with 100 mg. of Norvir
Sep 2, 2007
Two studies recently reviewed at IAS 2007 indicated positive results for the use of Lexiva boosted with 100 mg. of Norvir instead of the standard 200 mg. (http://www.aidsmeds.com/articles/1667_12670.shtml). Are you boosting Lexiva with 100 or 200 mg. of Norvir in your practice? Thanks.
Response from Dr. Young
Thank you for your post.
Provided that we're talking about patients with wild type, drug susceptible virus (confirmed by genotypic or phenotypic testing), then we've largely switched to using a single 100 mg ritonavir (Norvir) to boost fosamprenavir (Lexiva, Telzir). The resulting 3-pill, once-daily PI regimen (component) is very well tolerated and doesn't have the dietary restriction of the other commonly prescribed first-line PI, atazanavir (Reyataz). BY
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