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early signs drug resistance
Aug 15, 2007

my resihusband has been HIV + for 13 years and his viral load has been undectable for a long time. resntly he switch to Atripla . Now on his latest lab report his viral load is 52 but his cd4 count has icreased from 700 to 840. Is this early signs of drug resistance

Response from Dr. Young

A single viral load test of 52 with previous undetectables is almost certainly not a sign of early drug resistance, but rather of what we call "blips"-- elevations that nearly always return to the undectable level. Often, these are the result of minor activation in the immune system- as caused by minor infections (like sinus infections or herpes) or vaccinations. Several clinical studies have shown us that there is no long-term implication of having a blip, so long as the next load tested is undetectable.

Hope this helps. BY



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