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Atripla on empty stomach
Mar 28, 2007

I amtaking Sustiva/Truvada with dinner each night without difficulty or side effects. Planning to switch to Atripla, I see that it is recommended that Atripla be taken on an empty stomach. I hate to change my routine that has me at 100% compliance. Is there a drug absorbtion reason that Atripla must be taken on an empty stomach? Is it solely to avoid efavirenz related side effects (of which I have none)? I appreciate your assistance.

Response from Dr. Young

Thank you for your post.

You're correct, the primary reason to take efavirenz (Sustiva, Stocrin, part of Atripla) on an empty stomach is to decrease the risk of side efffects (food increases efavirenz absorption). If you're doing well with your medications and routine, I'd just keep doing what has already been successful.

Hope this helps, BY



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