|Which drug to start with for hiv/hcv coinfection?
Feb 7, 2007
was diognised hcv and hiv coinfection on February 2006.( CD4:650 viral load:67.5000 hcv-rna: 350.000u ) i started pegasys and copegus theraphy and took them for 10 months but no response.my tests on january 2007 are cd4:400 hiv-rna: higher than 100.000 and hcv-rna:1.500.000 u. want to start Haart! what do u think the best drugs to start within these conditions? My doctor advice me to take Kaletra and combivir, is atripla a better choice for coinfeceted patient? thanks
Response from Dr. Wohl
If you are off of HCV therapy and have no plans to restart I do not think there is any particular HIV regimen to avoid. Some would stay away from Nevirapine given concerns regarding this drug and liver function and certainly men with a CD4 count above 400 and women with a CD4 greater than 250 (HCV+ or - ) should not take nevirapine except under extraordinary circumstances.
switching to Viramune (Follow Up)
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