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wild versus mutated
Nov 26, 2006

is it true that someone who has a wild or non resistant strain tends to drop cd4's more rapidily to to the fact the wild virus is more aggressive? by the same rational is it true that a strain that is mutated or has some resistant is a more slow moving virus?

Response from Dr. Young

Thanks for your post.

For the most part, you're correct. Drug resistant virus can definitely cause CD4 damage ; just as wild type virus. There are some data that suggest that some types of drug resistant virus have impaired ability to replicate (replication capacity)-- such virus is somewhat less likely to cause rapid declines in CD4 cell counts. BY

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