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resistant or not
Sep 19, 2006

after taking norvir for at least four years now my genetype test clearly says i am resistant. Recently my doctor changed my meds to include Aptivus. Why then should I now have to take even more Norvir to boost the Aptivus. How can Norvir boost anything if I am resistant. What does boost mean is something lacking in the Aptivus? Is this a part of salvage therapy? (tcells 112) Thank you

Response from Dr. Young

Thanks for your post.

No, ritonavir (Norvir) retains its activity as a booster for tipranavir (or other PIs), even when the virus has genotypic evidence of resistance.

Typically, tipranavir is used for persons who have a high level of PI resistance. Though subjective, some call this situation "salvage therapy".

Best of luck, BY



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