Truvada vs Combivir
Jul 23, 2006
I was diagnosed in May of 05, CD4 21 and VL >750,000. Been on Combivir and Kaletra since and 100% adherant. VL has been U/D since first labs and cd4 now 242. I have concerns about the AZT in Combivir and have expressed a desire to switch from Combivir to Truvada. The issue is that when I was hospitalized, they found out that I was born with only one kidney. From what I can glean, Truvada puts a strain on kidney function. Is this true?
Response from Dr. Wohl
Truvada contains a medication called tenofovir. Tenofovir has been linked anecdotally to kidney problems in a few patients. However, in reviews of data from many patients taking the drug serious kidney problems have been found to be very rare. Minor changes in the filtering ability of the kidneys are more commonly seen but are thought by most to be of questionable clinical significance.
Of course, there are no data in people with only one kidney. If your renal function is good, I do not see a problem and close monitoring should detect any changes. I think whether to go on Truvada is something you, your nephrologist and HIV doc should discuss together.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Swelling In The Throat And Thrush
- How Effective Are Condoms Against Hiv?
- Can You Get Hepatitis C From Eating Something With Infected Blood On It?
- Will The Hpv Vaccine Help People Who Are Already Infected?
- When Does The Hair Loss Stop With Syphilis?
- What Is The Most Common Medication Prescribed For Gonorrhea?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.