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Suggestion & Lipodystrophy

Jul 19, 2006

Dearest Gerald, Since 1997 I have been diagnosed. Started with Crixivan/Epivir/Retrovir, then exchanged Crixivan to Viracept due to ill feelings. In 2002 I developed resistance to epivir and viracept so switched to Ziagen/Viramune/Retrovir which worked perfect for three years. I am now developing Lipodystrophy and dangerous levels of colesterol. Can you agree that a good solution could be a change to Sustiva combided with something else to avoid further fat problems. What do you suggest ? Thank you.

Response from Dr. Pierone

Hello and thanks for posting.

It sounds like you need to change therapy, but a switch from Viramune to Sustiva would not be a logical choice since cholesterol levels tend to run a bit higher with Sustiva. But there are data which demonstrate beneficial effects on cholesterol and lipodystrophy when Retrovir (AZT) is changed to Viread. Let us know how things turn out with whatever new regimen you switch to. Best of luck!

Meds or no Meds

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