Jun 14, 2006
I am currently on Kaletra, Zerit, and Viread. Would i ever be able to go to Kaletra monotherapy? If so would I have a higher chance of possible resistance to Kaletra since I have taken it with other meds?
Response from Dr. Wohl
There have been a few studies now of Kaletra monotherapy (used alone). The most celebrated looked at a small number of people started on Kaletra only. A handful of others took individuals already on HIV meds who had viral loads that were undetectable and switched them to just Kaletra. These studies have demonstrated some impressive results.
That you are on other meds in no way should compromise the activity of Kaletra - whether taken alone or with other HIV therapies.
I wonder if the attraction of Kaletra monotherapy is the simplicity of taking only one med or something else (less co-pays). If this is all about convenience, an option is to get rid of that old twice a day Zerit and switch to Truvada which gives you the tenofovir plus FTC and is only one pill a day. This one extra pill in addition to your 4 tablets of Kaletra is well worth it in terms of security.
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