add to hiv E. Africa Q
Jun 8, 2006
Following up to the question on June 4th regarding the A and D clades of HIV infection in East Africa...I became infected in Tanzania last January (05) and have already dropped in CD4s to under 200 - my VL is 399,000. I read the link regarding the D Clade and am wondering if that is what could have made me progress so fast from initial infection to an AIDS diagnosis. Should I ask my Dr. to run a test for the D Clade (and can he now that I have started meds?)? He did a Genome test and found the strain was not resistant to any medication but I am not sure that is the same thing. If it is D Clade type then will it respond to treatment the same as any drug-naive strain?? Thanks for any info - this forum is wonderful!
Response from Dr. Young
Thanks for your post.
I think that you may already have the answer to your question in the resistance test. Most resistance tests also report the HIV clade-- ask your doctor about your test results. Among patients with non-B virus, I'll tend to order a phenotype, if financially possible, since most of the genotypic interpretations are based on data derived from clade B virus.
That said, whenever I start a treatment regimen, particularly among non-B clades, I'm very attentive to the decreases in viral load. If they're heading down, then I'm satisfied. If not, I'll be asking a lot of questions.
I hope this helps, BY
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