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Duration of drug combinations
Jun 7, 2006

For persons who are trying treatment now for the first time with at least a 250 t-cell count, how long does a drug regimen usually last before becoming drug resistant? two years? 5 years? 10 years? longer? Thanks for your answer.

Response from Dr. Young

Thanks for your post.

Patients who remain optimally adherent to a well chosen (by baseline resistance testing) HAART regimen have a greater than 90-95% of having success. Adherence is much more important than baseline CD4 counts (at least in this range) in predicting the rate of treatment failure or drug resistance.

For patients who have viral suppression after the first year of treatment, it's very, very rare to see failure and resistance in subsequent years. BY

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