|Drug interaction with acyclovir?
Jun 4, 2006
I have been on sustiva and truvada for almost a year. VL was undetectable and CD4 was over 800. Then I had a herpes outbreak, so I took a 5 day course of acycovir (200mg, 5x a day) as prescribed. Shortly after, my VL was up to 3,300. Thankfully, about 6 weeks later, it was back to undetectable. Could the herpes have a part in the blip up? Is acyclovir counterindicated when taking sustiva or truvada? The reason I ask is that the pharmacy insert that came with the Truvada said to make sure your physician or pharmacist is aware if you are on any other antiviral medication, and specifically mentioned acyclovir. Thanks, as always, for your advice.
| Response from Dr. Pierone
We always try to explain an anomalous viral load spike by blaming it on an intercurrent viral infection. In your case the herpes outbreak may well have been the inciting event. Herpes simplex virus can act as a trigger for activation of HIV-infected cells and subsequent increase in viral load. There is no problem using acyclovir along with Sustiva and Truvada. The expectation is that with HSV suppressed you should have an undetectable level of HIV RNA next time. If things don't return to undetectable then you would need to have a viral resistance test. Best of luck!
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Itchy Scrotum After Touching Vaginal Fluid Sign Of HIV AIDS
- Pain In Penis After Getting Scratched Worried I Have HIV
- Psoriasis After Anal Sex Worried I Have HIV
- Human Immunodeficiency Virus Linked To Osteoarthritis
- Can Bacterial Vaginosis Cause Vaginal Bleeding?
- Can You Get Warts With Gonorrhea?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.