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blip or resistance?
Apr 28, 2006

I have been undetectable for 2years now. On trizivir and viramune but after concerns of some fat loss I was put on epzicom. Right before I changed meds I got a "blip" of 150. Then checked again was at 50. Then I changed the meds and now at 240,w/ t-cell count 840. I am afraid I have gotten resistant to my meds. I am fearful that the virus will just go up and up no matter what I do. Should I be scared or could I once again be undetectable?

Response from Dr. Pierone

Hello and thanks for posting.

Blips are temporary increases in viral load readings in people who are usually undetectable. Blips rarely evolve into virologic failure and drug resistance unless adherence is poor. Since you had a blip before changing the regimen, the switch is not responsible.

So chances are that you are not developing resistance (unless adherence has been poor on this regimen) and should expect an undetectable viral load again. Let us know how things progress and best of luck to you!

starting meds again, help!gain help!
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