Apr 6, 2006
Dear Doctor Young,
A few weeks ago I asked you a question about new side effects (light peripheral neuropathy, nausea, rash, feeling tired...) after a change in meds from epivir to emtriva (both with sustiva and viread). I had no side effects at all before the change.
You mentioned in your reply that there are a minority of people that, like in my case, did not tolerate emtriva as well as they had done epivir.
I stuck with emtriva a few weeks longer while I waited for my appontment with the doctor to ask him a change back to epivir. But in the mean time most (if not all) of the side effects have resolved. I am not feeling that horrible tingling in my hands, nor am I feeling nausea and I am feeling less and less tired.
Apparently peripheral neuropathy and lypodistrophy are both thought to be related to toxicity in mithocondria. I was wondering whether, even though the side effects have resolved, I should still go back to epivir in case emtriva is still damaging nerve and fat cells, or at least, more so than epivir was.
Is that a silly question?! ;-)
Thanks so much again!!
Response from Dr. Young
Thanks for your follow up and question. There are very few treatment-related silly questions here.
Sounds like you simply had an unusual and short-lived side effect of the emtricitabine (FTC)-- as such, I don't think that I'd worry about having long-term issues (at least the same ones) and you can proably just continue on Truvada.
I'd mention your symptoms and their improvement to your doctor, just to be sure.
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