truvada and viramune
Jan 28, 2006
I'm just starting to take meds. Is truvada and viramune a good drug combination for first line therapy? I've always heard and seen first line therapy should be boosted with a PI.
Response from Dr. Young
Thanks for your post.
I think that both points are not incorrect. Truvada + nevirapine would be a perfectly reasonable alternate first-line non-nuke-based treatment. I'd be cautious to use this in persons with higher CD4 counts (women >250, men >400) because of an increased risk of liver toxicity.
You're also correct in the idea that many doctors (self included) have adopted ritonavir (Norvir)-boosted protease inhibitors as first-line treatments, because of their resistance profiles and the advent of easier-to-take, better tolerated PIs.
If in doubt, I'd talk to your doctor about your treatment options.
Good luck, be well. BY
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