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cd4% to cd8%

Jan 25, 2006

I was reading that in a hiv- person cd4 cells are about 2 to 1 to cd8 cells but in someone infected with hiv it is reversed to 1 to 2 is this right away or does this gradually happen over years? also I have read that the average cd4 loss per year is between 40 to 100 cells, what about the first year, I thought there was a larger decrease? thank you and happy new year!!!

Response from Dr. Young

Thanks for your post.

I think that in general, your assumptions are correct. The changes are more acute in the first year of infection, then slower over years. The main thing is that there is a lot of person-to-person variation in the rates of CD4 change-- coming up with a hard number for the rates of change is difficult. BY

are all meds hard on liver

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