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Body Weight
Jan 19, 2006

What role does body weight play in regards to the dosage of HARRT. Will the same dosage work as well in a person say 135 lbs as it would someone 335 lbs? With that being said, is it possible to have too much or too little of the meds in your system at a time and what are the consequences of being over medicated?

Response from Dr. Young

For the most part the dose of medications are based not on the patient's actual weight, but their ideal weight-- since most persons who weigh 300 pounds are likely not at their ideal weight, the dose of HAART medications doesn't need to be changed.

To be fair, this situation is not frequently encountered and not fully studied in HIV patients. If I'm in doubt about dosing, I'll try to get therapeutic drug level monitoring (TDM). BY



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