Nov 27, 2005
I am currently on Sustiva and Combivir. I would like to get pregnant within the next six months. Should I switch off of this combination (even though it has been effective) and, if so, when would be a good time to do so?
Response from Dr. Young
Thanks for your post.
It's great to hear that you're well-- well enough to consider planning a family.
The only issue with your current regimen is the use of efavirenz (Sustiva, Stocrin) during pregnancy. The problem is that efavirenz is not recommended during pregnancy because of risk of fetal injury. For this reason, if your seriously interested in becoming pregnant, I'd recommend switching to a different "third" drug.
Many maternal-fetal HIV experts recommend the use of a protease inhibitor during pregnancy- recommendations vary, but some use nelfinavir (Viracept), while others will use a boosted PI, such as Kaletra. All would probably recommend that you continue on your Combivir (AZT+3TC), since AZT has been strongly associated with protection against mother-to-child transmission of HIV.
When to switch is not really critical, other than to do so several weeks before becoming pregnant, to allow the efavirenz to be completely out of your system.
Good luck, let us know how things turn out for you. BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.