My drug regimen includes Viread and Combivir which I have been on for the past 15 mos when I was diagnosed. My lab results show viral load is undetectable and cd4 is up to normal, however, I've been suffering from severe nausea and vomiting. Initially it was on and off, but for the past 2-3 mos it has been constant. Tried Ginger and Zofran without much help. I went though audio test to rule out any ear problems and x rays and MRI's to rule out Osteomyelitis(before I get severe nausea and vomiting, it always starts with pain and tenderness of an ankle). Now, my physician is recommending for a lumbar puncture for possible virus. Do you have any idea what is causing these symptoms? Is it possible that these symptoms are caused by medications? These symptoms seem worse in the morning and at night 1-2 hours after I take my meds. Any advise you can offer will be greatly appreciated.

If the nausea began immediately when you started the medications then I would suspect they are the cause. I would talk to your doc about stopping the meds for a couple of weeks and seeing if the nausea resolves as an ultimate test.

If this turns out to be the case you can try to introduce the meds one by one (start one for a few days then if no nausea, add the other). This should not risk resistance and will let you see which one is the culprit.

DW DW