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lipitor vs. pravachol
Oct 8, 2005

Aren't Lipitor and pravachol the same type of cholesterol lowering drug? And if so, wouldn' you be taking one or the other not both?

Response from Dr. Wohl

These are both drugs in the same class (statins). One would not take both.

They are different in their potency and drug interaction potential.

Lipitor (atorvastatin) is more powerful but does have interactions with HIV meds. Protease inhibitors can raise the level of this drug so starting with lower doses is recommended. NNRTIs like Sustiva can reduce the level of this drug (and other statins too).

Pravachol (pravastatin) is not as potent but does have less drug interactions than Lipitor.

I prefer Lipitor for my patients with HIV infection and I try to dose carefully.

DW



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