CD4 %, AIDS??
Sep 23, 2005
Hi Dear Doctor,
My latest lab results are the following: CD-277, VL-30,000, CD4%-13. At this point, my Doctor advises that I still hold off on the medications, do you agree Doctor? With a percentage of 13%, does this not constitute an AIDS diagnosis? Am I at risk for an opportunistic infection? Please answer Doctor. Thank you very much!
Response from Dr. Young
From the CDC classification system, a CD4% of 13 meets the criteria for AIDS. As such you are at some risk of opportunistic infections and if you were my patient, I'd be discussing starting on antiretroviral therapies in the near future. BY
Here's the CDC 1993 classification system for AIDS:
A diagnosis of AIDS is made whenever a person is HIV-positive and: he or she has a CD4+ cell count below 200 cells per microliter OR
his or her CD4+ cells account for fewer than 14 percent of all lymphocytes OR
that person has been diagnosed with one or more of the AIDS-defining illnesses listed below.
Candidiasis of bronchi, trachea, or lungs (see Fungal Infections) Candidiasis, esophageal (see Fungal Infections) Cervical cancer, invasive Coccidioidomycosis, disseminated (see Fungal Infections) Cryptococcosis, extrapulmonary (see Fungal Infections) Cryptosporidiosis, chronic intestinal (>1 month duration) (see Enteric Diseases) Cytomegalovirus disease (other than liver, spleen, or lymph nodes) Cytomegalovirus retinitis (with loss of vision) Encephalopathy, HIV-related (see Dementia) Herpes simplex: chronic ulcer(s) (>1 month duration) or bronchitis, pneumonitis, or esophagitis Histoplasmosis, disseminated (see Fungal Infections) Isosporiasis, chronic intestinal (>1 month duration) (see Enteric Diseases) Kaposi's sarcoma Lymphoma, Burkitt's Lymphoma, immunoblastic Lymphoma, primary, of brain (primary central nervous system lymphoma) Mycobacterium avium complex or disease caused by M. Kansasii, disseminated Disease caused by Mycobacterium tuberculosis, any site (pulmonary or extrapulmonary) (see Tuberculosis) Disease caused by Mycobacterium, other species or unidentified species, disseminated Pneumocystis carinii pneumonia Pneumonia, recurrent (see Bacterial Infections) Progressive multifocal leukoencephalopathy Salmonella septicemia, recurrent (see Bacterial Infections) Toxoplasmosis of brain (encephalitis) Wasting syndrome caused by HIV infection
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