Fuzeon for PEP
Aug 29, 2005
There is talk about Fuzeon being used for hiv PEP. Do you think its medically posible to achive this?
Response from Mr. Kurtyka
I'm not sure what you mean by "medically possible." Theoretically, if you can prevent HIV from ever attaching to a CD4 cell during initial exposure to HIV, this would be a great war on HIV infection. Some of the problems associated with using Fuzeon for post-exposure prophylaxis could include the expense compared to other traditional agents (that we already believe work quite well), plus the potential difficulty of twice a day injections. People would probably still have to take one or two other "conventional" antiretrovirals commonly used for PEP. A lot of people who a prescribed a 4 week couse of PEP don't complete it due to side effects associated with the meds. Not sure how adherent people would be to twice daily injections.
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