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Valproic acid
Aug 16, 2005

Just a quick question wondering whether the panel had any thoughts on the recent report in The Lancet (August 13 issue) suggesting that a combination of Abbott Laboratories' Depakote (divalproex sodium) formulation of the drug and Roche's HIV entry inhibitor Fuzeon (enfuvirtide) - given on top of HAART - can reduce latent HIV infection by 75% in three of four patients tested. Could this be one effective way of purging dormant virus particles?

Response from Dr. Wohl

Maybe. David Margolis, the lead investigator of this study, has relocated to my university in North Carolina and will be exploring this novel and exciting approach further. Trust me, there will be more to come.

DW



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