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3rd Generation HIV meds
Jul 21, 2005

Doctor young:

Hi. Is science working on a 3rd generation of HIV drugs?

Thanks for consideration of my question.

Mark

Response from Dr. Young

Mark- Thanks for your question.

It's rather difficult to define first-, second- and "third-generation" medications for HIV. But to provide a crude summary, the answer is yes.

There are new drug targets that are actively being explored-- HIV integrase (integrase inhibitors), HIV co-receptors (CCR5 inhibitors), maturation inhibitors and lest we forget, therapeutic vaccines. We also have the first of a new generation of HIV protease inhibitors, with tipranavir (and others in the pipeline).

It certainly looks at this time that CCR5 entry inhibitors may very likely be the next class of medications.

--hope this helps, BY



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