switch to viramune?
May 14, 2005
Dear doctors , would it be advised to switch to viramune with 1100 t cells. I am currently on lexiva/truvada(since january) and tolerating it ok, but,I am accumalating fat around my stomach(gained 20 pounds).I was on sustiva could not take it.please advise. thankyou.
Response from Dr. Pierone
Protease inhibitors like Lexiva have been linked to a greater risk of abdominal fat accumulation (lipohypertrophy). A switch to Viramune might be effective, but with such a high CD4 count there would be a greater chance of liver toxicity. This raises the next question - why are you on antiretroviral therapy with such a high count and do you actually need to be on medications at all?
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