The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

Choosing Your MedsChoosing Your Meds
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  • Email Email
  • Glossary Glossary

acute infection, considering a clinical trial

May 13, 2005

Dear Doctor:

I am a 25 year old male who has recently (within the past 5 weeks) been infected with HIV. I've read various articles that all basically are inconclusive as to the benefits of early treatment during the acute stage of initial infection. I live in the U.S. and lack insurance, therefore I'm considering participating in a clinical trial. The one which seems most appealling to me is one in which the study group is randomly divided into two groups: Group 1 gets Cyclosporine A for four weeks, in addition to a 48 week regimine of Trizivir and Kaletra; Group 2 gets only the Trizivir and Kaletra. My question can be divided into two parts: "Is Trizivir and Kaletra a good initial therapy? " and "What is your opinion on the potential of Cyclosporine A to reduce potential damage to the immune system/cd4 cells?

Response from Dr. Pierone

This is certainly an important study - a previous trial of cyclosporine plus HAART in primary HIV infection showed very promising results. The use of Trizivir and Kaletra is a very aggressive regimen and not one that would likely be used outside the context of a experimental protocol. My opinion is that immune modulators like Cyclosporine may ultimately play a role in HIV therapy and controlled studies of this strategy are long overdue.

Hiv+ behavior
Positive for over 22 yrs/just starting treatment

  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint