acute infection, considering a clinical trial
May 13, 2005
I am a 25 year old male who has recently (within the past 5 weeks) been infected with HIV. I've read various articles that all basically are inconclusive as to the benefits of early treatment during the acute stage of initial infection. I live in the U.S. and lack insurance, therefore I'm considering participating in a clinical trial. The one which seems most appealling to me is one in which the study group is randomly divided into two groups: Group 1 gets Cyclosporine A for four weeks, in addition to a 48 week regimine of Trizivir and Kaletra; Group 2 gets only the Trizivir and Kaletra. My question can be divided into two parts: "Is Trizivir and Kaletra a good initial therapy? " and "What is your opinion on the potential of Cyclosporine A to reduce potential damage to the immune system/cd4 cells?
Response from Dr. Pierone
This is certainly an important study - a previous trial of cyclosporine plus HAART in primary HIV infection showed very promising results. The use of Trizivir and Kaletra is a very aggressive regimen and not one that would likely be used outside the context of a experimental protocol. My opinion is that immune modulators like Cyclosporine may ultimately play a role in HIV therapy and controlled studies of this strategy are long overdue.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Jock Itch After Vaginal Sex With Condom What Are The Chances Of HIV
- Sore On Mouth After Handjob Worried I Have HIV
- White Spots After Blowjob Worried I Have HIV
- White Tongue After Open Mouth Kissing Worried I Have HIV
- Does Any Std Affect Your Urine Flow?
- How Often Does Chlamydia Cause You To Be Sterile In Women?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.