|CCR5 Inhibitors and future
Apr 18, 2005
Dr. Wohl, I have not started therapy yet and hope that I won't have for a while. With that being said, you mentioned CCR5 inhibitors and that they will be the next big thing in HIV therapeutics. If I am able to wait until they come out, how will therapy be different in the most optimistic view? Also, how do you envision the change in therapy in a neutral view?
| Response from Dr. Wohl
Both my neutral and optimistic selves are not sure what this new group of drugs will bring. I think it is exciting that new classes of agents are being developed and that these will work in novel and maybe complimentary ways that open up possibilities. We have been stuck by the historical development of HIV medications into a mold wherein we use certain drug classes first and others later.
With new classes and subsclasses of antiretrovirals we will have a greater number of options and more room for creative application of these drugs that, I suspect, will lead to initial combos that look nothing like what we are using now.
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