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Is that 400 in the morning or in the evening?
Feb 11, 2005

"I'd be thinking about starting with CD4 counts at or about 400." Is that 400 in the afternoon or 400 in the morning?

Do you agree that the 60-200 variation between morning and evening needs to be looked at more seriously?

Response from Dr. Young

I'm not sure that the variability needs to be looked at more seriously, but rather the understanding that there is variation-- if one simulateously looks at CD4 absolute counts (that do have significant variation) and CD4 percentages (which have less variability) it becomes easier to track some of the AM and PM variations. CD4 percentages tend to have less diurnal variability than absolute counts. BY



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