|Side Effect Switch
Nov 13, 2004
I am planning on switching, for side effect reasons, from Epivir/viread/Kaletra to Sustiva/Truvada after 12 months on the PI regimen. The relevant stats are T4 nadir of 292 and viral zenith of 1.06 million. Currently undetectable (<20, for 3 months and ~700 T4). Any thoughts or caveats? Thank you
| Response from Dr. Pierone
The main thing is to be aware of the vivid dreams that can occur with Sustiva as well as a sedated or "drugged" feeling from this medication. These side effects typically last for days to weeks and gradually disappear. Otherwise, Sustiva is very well tolerated and likely has fewer long-term side effects than Kaletra. The change from Viread/Epivir to Truvada should go off without a hitch. Best or luck!
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