Your advice again
Oct 24, 2004
Hi doctor Young! It is me Dav again.Thank for your immidate respod on my question on trizivir and norvir on october,16,2004.I live in Africa and the problem is limitation of drugs and their costs.The other alternative which I have is to start with Reyataz,Norvir,Epivir and Retrovir.What is your advice and their daily dose? Thank,Dav.
Response from Dr. Young
Thanks Dav for your follow up and clarification.
I can now understand your initial question with greater clarity-- as such the issue with ritonavir is that it should be dosed (as a single PI) at 600 mg twice daily. This can be problematic, largely because of the frequent gastrointestinal side effects.
A entirely once-daily combination of atazanavir (300 mg, Reyataz) with ritonavir (100 mg, Norvir) with 3TC (300 mg, Epivir) and AZT (Retrovir) should be very effective and much better tolerated that the Norvir-alone PI regimen that you've mentioned before. Moreover, while the ritonavir-boosted atazanavir regimen has yet to be fully studied in treatment naive persons, boosted PIs are clearly gaining popularity here in the US. The once-daily option is also clearly an advantage.
The key to any atazanavir regimen is knowing that the medications (while once-daily) must be taken with meals and antacids should be taken only with your doctor's supervision, since both have the potential to dramatically lower your atazanavir drug levels (and hence the drug's potentcy).
I hope this helps, let us know what you and your doctor decide and how things go. I'm sure that this information will be very important to many of our readers. BY
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Vomiting After Open Mouth Kissing Worried I Have HIV
- How Long After Unprotected Sex Does It Take To Know You May Have A Std?
- Once You Have A Std Do You Ever Get Rid Of The Std
- What Vaginal Infections Does Metronidazole Treat?
- Any Case Of HIV By Spitting Blood In Eyes
- Can Kaposi's Sarcoma Be The First Sign Of Hiv?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.