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Restructuring Epzicom/Sustiva Timing

Oct 24, 2004

I'm recently diagnosed (cd4 290, VL 330,000) healthy, never an OI and I've just started treatment with the once-per-day epzicom & Sustiva. I began my dosing at 9:30pm to leave me realatively clear-headed for work in the morning, but I'm finding this start time prohibitive to evening activities & often dinner when I work late. How much wiggle room do i have to delay dosing till 10 or 10:30pm? I don't want to risk letting levels drop so soon in my treatment. The only troublesome side-efect I seem to have is a general feeling of malaise all day. Is this common & does it subside?

Response from Dr. Young

Thanks for your post.

You've got plenty of "wiggle" room for dosing your once-a-day regimen. Shifting your dose from 9:30 to 10:30 shouldn't pose any problems with drug levels.

As for the malaise or other side effects, most initial side effects gradually fade over time. If your's don't let your doctor know, there may be a number of things to do to manage your specific issues that might make your quality of life a little better.

Good luck, BY

Starting Treatment
bloating with sustiva/combivir

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