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viramune + prednisone

Aug 31, 2004

A friend was on Viramune for 5 dys and developed a rash. His Dr told him to wait a few days then start the drug again. He did, and the rash became worse. He went to his local ER and was put on Prednisone. The rash became MUCH worse to the point of necrosis. Why ? Is this common ? Can he still take Viramune ?

Response from Dr. Lee

It is not generally recommended to treat the rash associated with Viramune by using prednisone if the Viramune is continued. The rash does tend to get worse if the drug is continued. It sounds like your friend needed to discontinue the medicine, which I hope he did. This is a severe reaction which sometimes (not often) happens. The more common rash associated with Viramune disappears without stopping the medicine. This is one reason it is important to see an experienced, knowledgable HIV-treating doctor.

Be well.

Combivir and Viramune
Can I go back again?

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