Advertisement
The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol
   
Ask the Experts About

Choosing Your MedsChoosing Your Meds
          
Rollover images to visit our other forums!
Recent AnswersAsk a Question
  
  • Email Email
  • Glossary Glossary


1st time regimen
May 13, 2004

I am from a small town w/ limited HIV accessability, however do see a Dr. w/ some knowledge about HIV.

Have had HIV 6 years, no health problems, 375 T-cell, 115,000 Viral.

Dr. wants me to start meds w/ Epivir, Sustiva, & Zerit. A friend has cautioned me about this combo, especially the Zerit.

with the correct advice, I will share w/ my Dr. Any insight on the better combo would be greatly appreciated. I am trying to learn, but it is hard to choose w/ so much info.

ThanX for your time and excellant service to the communities in middle AmeriKa. James

Response from Dr. Young

Thanks for your post.

I'd agree with your friends that in 2004, stavudine (d4T, Zerit) would probably not be my first choice as a component of initial therapy. This is not to say that d4T hasn't been a very popular and generally well tolerated drug, but rather that recent revelations about d4T's side effect profile (increased risk of lipodystrophy, elevations in cholesterol and risk of neuropathy) and the advent of alternatives, such as abacavir (Ziagen) or most recently, tenofovir (Viread) relegate d4T to the alternative first line drug in my clinic (and many clinics across the US). The use of either of these meds with 3TC (Epivir) and efavirenz (Sustiva) would be very supportable.

There are a number of large, prospective clinical trials that have evaluated abacavir/3TC/efavirenz or tenofovir/3TC/efavirenz. All have shown excellent tolerability and potency and offer the once-daily option that d4T currently does not. Furthermore, soon, we'll see an abacavir/3TC and tenofovir/FTC (a cousin of 3TC) fixed dose combination tablet, offering the possibility of a two pill, once-daily option. I'd vote for one of these possibilities.

Thanks for reading, keeps us informed of how things turn out. BY



Previous
anti-HIV gene
Next
Beginning in L.A.

  
  • Email Email
  • Glossary Glossary

 Get Email Notifications When This Forum Updates or Subscribe With RSS


 
Advertisement



Q&A TERMS OF USE

This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint

Advertisement