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changing meds

May 3, 2004

I have hiv for 20+years.I have been on fortovase,norvir,and combivor since they were approved about 8 years.I've cleared hep c. I have diabetes and high colesterol and would like to know if there is a better combination I can take. My doctor doesen't want me to change but I'm having trouble controlling these. My vl has been undetectable since I began meds. What is your opinion about this.

Response from Dr. Lee

The combination you are taking is obviously working and thus explains some hesitancy to change. However, there are certainly some combinations which utilize "lipid friendlier" protease combos. For example, Reyatase (atazanivir), may lower cholesterol and triglyceride levels. Other "protease sparing" regimens such as Combivir with either Viramune or Sustiva are also alternatives.

Congratulations on maintaining this regimen for 8 years. Talk to your doctor before you get too weary and start missing doses, etc.

Be well.

Once or twice?

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