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Dr Recommendation Second Opinion
Mar 28, 2004

Dr. Pierone,

I was diagnosed as HIV-Positive in early February 2004. Since then, I've learned that my CD4 count is 253, and my viral load is 61,000.

I reside overseas in Japan, where treatment options are, according to my physician, about "90 of what they are in the US."

He suggests I start a regimen of Combivir + Efavirenz (Sustiva). Is this a typical regimen for individuals just commencing treatment?

Thank you for your assistance.

Response from Dr. Pierone

I think that Combivir and Sustiva may still be the most common starting regimen in the United States and has demonstrated long-term effectiveness. There is a trend towards once daily treatment of HIV infection so once daily Viread, Epivir, and Sustiva is becoming more common. One concern with Combivir and Sustiva is that it may blunt CD4 increases (from the AZT component of Combivir) compared to other regimens that omit the AZT.



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