|Immune to HIV
Mar 23, 2004
Hypothetically speaking, I was just wondering, if someone were immune to the HIV virus, like those prostitutes in The Gambia, would they still be able to transfer the virus? I guess it would be similar to a female who passes on the hemophiliac gene to her son, although it doesn't affect her. She's only a carrier.
Response from Dr. Pierone
If someone were completely immune to HIV they would not transmit. But if infection became established, but non-progressive due to relative immunity, this could lead to a carrier state of sorts. In this case, productive viral replication and shedding in genital secretions could allow for transmission to an intimate partner or to her infant at birth. This would not be considered a "carrier" scenario in the classic genetic sense.
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