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Non-Progression
Mar 23, 2004

I have been HIV positive for 18+ years. For at least the last 15 years, my t-cells have been around 400, and since the test became available, my viral load has been around 2000 (for both results, give or take 10 percent or so for any given test). I've never had any symptoms or other manifestation of HIV. Doctors in the past recommended various med regimes, which I rejected as unnecessary since I apparently was not sick. At this point, I get my labs done annually, and go see my doctor simply so that we will recognize one another if we were to bump into each other on the street.

My question is: Where can I find more information about people in my situation? Web searches, and searches of this and other sites, provide no information on non-progressors such as myself. I assume that I hardly am unique; there must be others in a similar situation. I'd appreciate some information and especially a link or two. Thanks very much.

Response from Dr. Pierone

I don't have a link, but you are not unique. There are many people that have had HIV infection documented for many years, but don't progress, so called "long-term non-progressors". Basic research continues to uncover the variety of reasons why some people don't progress with HIV. This is an important area of research because as the correlates of protection are discovered, this will lead to more rational design of immune-based therapy as well as new targets for antiviral agents. There have been some recent reviews on LTNP; I will locate them and post.



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