|Can one become un-resistant to meds formerly resistant to
Mar 22, 2004
can a person become, after a while and after having switched to other meds, un-resistant to a med that he had become resistant to? I've never seen this question asked or answered but then i've never read everything in these sites. i certainly think it's a very valid and important question not only for myself but for everyone.
| Response from Dr. Pierone
Yes, but really no. Viral breakthrough that arises while on therapy may lead to development of viral resistance to a specific antiretroviral medication. Once this occurs, these resistant viral quasi-species persist for prolonged periods of time. If the medication in question is stopped, the resistant mutations may seemingly disappear on follow up genotype testing. But the resistant mutations are actually present in low level in plasma or in a dormant state in immune cells. The practical implication is that if the original medication is reintroduced, viral resistance typically returns quite quickly. This is an important question and to a large extent has been answered by some of the pre-salvage STI studies that have been reported on in the last year.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Itchy Rash After Oral Sex Form Sex Worker Does It Mean I Have HIV
- Itchy Scrotum After Erotic Massage Sign Of HIV AIDS
- Night Sweats After Unprotected Vaginal Sex Sign Of HIV AIDS
- Tingling Lips After Anal Sex Top Sign Of HIV AIDS
- White Tongue After Unprotected Oral Sex Without Ejaculation Worried I Have HIV
- After Treatment For Trichomoniasis How Should You Wait To Have Sex
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.