I started my treatment (kaletra and stocrin) 3 months ago and even though I have NEVER missed a single dose, I do however take my meds at different times of the day. For instance, sometimes I'll take my morning dose of kaletra at 10h30 and sometimes at 13h00 depending on when I have my first meal. I do this 'cos I get diarrhea if I take kaletra on an empty stomach so I always have to wait until I have eaten something and that doessn't always happen at the same time everyday. On weekdays I take my stocrin at about 22h00 but on weekends I take it around 12h00 midnight as I have a late shift job and I can't take it at 22h00 as it makes me a bit dizzy. Would this create problems of resistance even though I've never really missed a dose? Thank you

Thanks for your question.

Thankfully, for medications like the ones that you're taking, the timing of dosing is not too critical. For practical terms, I don't worry at all if doses are taken within a couple hour window of ideal.

Hope this helps, BY